The temporal and spatial distribution of strain associated with the Sevier orogeny in western North America is significantly different in the southern end of the belt, at the latitude of Las Vegas, Nevada, than farther to the north at the latitude of Salt Lake City, Utah. Reasons for these differences have been speculative as a lack of temporal constraints on thrusting in the intervening region hindered along-strike correlation across the belt. We determined a crystallization age of 100.18 ± 0.04 Ma for zircons extracted from a recently recognized dacite lapilli ash-fall tuff near the base of the synorogenic Iron Springs Formation. We propose the name “Three Peaks Tuff Member” for this unit, and identify a type stratigraphic section on the western flank of the “Three Peaks,” a topographic landmark in Iron County, Utah. Field relationships and this age constrain movement on the Iron Springs thrust and the end of the sub-Cretaceous unconformity in the critical intervening area to latest Albian/earliest Cenomanian. Movement on the Iron Springs thrust was synchronous with movement on multiple Sevier thrusts at ~100 Ma, indicating that the mid-Cretaceous was a period of extensive thrust-fault movement. This mid-Cretaceous thrusting event coincided with a period of global plate reorganization and increased convergence, and hence an increased subduction rate for the Farallon Plate beneath North America. The accelerated subduction contributed to a Cordilleran arc flare-up event and steepening of the orogenic wedge, which triggered widespread thrusting across the retroarc Sevier deformation belts. Additionally, based on temporal constraints and the strong spatial connection of mid-Cretaceous thrusts to lineaments interpreted as pre-orogenic transform faults, we suggest that temporal and spatial variations along the strike of the orogenic belt reflect tectonic inheritance of basement structures associated with the edge of the rifted Precambrian craton.