The calc-alkaline igneous rocks in the central Wasatch Mountains were emplaced between 36–30 Ma. They form a belt comprised of eleven stocks and the Keetley volcanic field aligned along the crustal suture between the Archean Wyoming province and accreted Paleoproterozoic terranes. Magmatism associated with this belt and its westward continuation into the Bingham mining district has been related to mid-Cenozoic extension. These rocks consist of two types of stocks based on texture: a western type, which is coarse grained, and mostly equigranular, and an eastern type (including the Keetley volcanic rocks), which is fine grained and porphyritic. The compositional variation in the western stocks (Little Cottonwood, Alta, and Clayton Peak stocks) forms three distinct compositional groups. The compositional variation in the eastern stocks is similar to the compositional variation in the Alta stock. Major and trace element variations in these rocks resemble those of subduction-related magmas. However, the high K2O contents and low εsr values are not consistent with this origin. These magmas formed from melting of mafic igneous rocks. We propose that magmas were generated by decompression melting due to gravitational collapse of the crust that had been thickened during Cretaceous to early Cenozoic deformation. Magmas rose to varying levels in the crust along an east–west lineament. The igneous rocks of the central Wasatch Mountains have εNd(t) similar to most of the Phanerozoic igneous rocks in the miogeocline (MG), but have significantly lower εSr(t). That anomaly has been explained as due to melting of a basement long depleted in Rb (Farmer and DePaolo, 1983, 1984). However, the Wasatch igneous belt rocks are high-potassium, calc-alkaline rocks and all have very similar incompatible trace element patterns, whereas only a few MG rocks are calc-alkaline or high potassium. Furthermore, in the MG rocks incompatible trace element patterns are variable. One possible explanation for the dilemma of long-time depletion of Rb in these high-potassium, calc-alkaline rocks is that the crust may have been recently charged with Rb and K during the Sevier-Laramide event (100–40 Ma) by dehydration of the subducting slab. This event was followed by melting during mid-Cenozoic collapse of the orogen (ca. 40–20 Ma). The source of the magmas was melting of mafic rocks in the lower crust. Some of these magmas ponded, formed magma chambers, and differentiated. Some involved little ponding and erupted directly on the surface in the form of the Keetley volcanic field. Continued melting and extension produced new magmas from a similar crustal source. These magmas were emplaced below a series of pull-apart structures associated with strike-slip displacement along an east–west suture. This suture may have been controlled by the Archean-Proterozoic boundary. Some magma bodies were emplaced quickly to the surface without significant fractionation. Others coalesced and fractionated over a protracted period of time. These magma bodies interacted with crustal rocks, and differentiated to relatively evolved compositions.