A legacy seismic data set from 2001 and 2011 was used for time-lapse interpretation over a Brazilian carbonate reservoir in Field-X of Campos Basin. The acquired 4D seismic data set was noisy and initially deemed to be uninterpretable. Pressure data were limited, and the initial simulation model was poorly calibrated. All of these challenges warranted the need to establish an interdisciplinary interpretation workflow. In this paper, we introduce a tiered integrated approach to optimize data value from multiple sources. The results of interwell connectivity from production data analysis were used as a basis for assignment of 4D signal confidence flags, which were later combined with simulation-to-seismic modeling of history-matched realizations, enabling interpretation efforts of the noisy 4D seismic data set. This integrated approach led to identification of the injected water front and a potential sweet spot for an infill well.