An intensive source of intermediate depth earthquakes has been located in northern Colombia. The activity of this source increased significantly between 1956 and 1966, but appears to be decreasing after 1966. The frequency-magnitude relation of the Bucaramanga earthquakes is anomalous, with fewer large earthquakes than expected. The distribution of determined hypocenters is the same as would be observed if all earthquakes originated in the same point source. Therefore it is concluded that the Bucaramanga seismic source consists of a volume, less than 10 km in radius, centered at 6.8°N, 73.1°W., and 150 km depth.