The Seismic Experiment for Interior Structures (SEIS) was deployed on Mars in November 2018 and began science operations in March 2019. SEIS is the primary instrument of the Interior Exploration using Seismic Investigations, Geodesy and Heat Transport (InSight) mission, which was launched by the National Aeronautics and Space Administration (NASA). The acquisition and control (AC) electronics is a key element of SEIS. The AC acquires the seismic signals of the two sets of seismic sensors with high resolution, stores the data in its local nonvolatile memory for later transmission by the lander, and controls the numerous functions of SEIS. In this article, we present an overview of the AC with its connections to the sensors and to the lander, as well as its functionality. We describe the elements of the acquisition chains and filters, and discuss the performance of the seismic and temperature channels. Furthermore, we outline the safety functions and health monitoring, which are of paramount importance for reliable operation on Mars. In addition, we analyze an artefact affecting the seismic data referred to as the “tick‐noise” and provide a method to remove this artefact by post‐processing the data.