General characteristics of seismic energy release of thrust earthquakes in Mexico have been reviewed in the past; however, a detailed analysis can contribute to a better understanding of the mechanisms that control its distribution along the Guerrero, Mexico, subduction zone. To address it, we obtain the source spectra of the 2012 7.5 Ometepec‐Pinotepa Nacional, the 2014 7.2 Papanoa, and the 2018 7.2 Pinotepa Nacional earthquakes, as well as of their aftershocks to estimate their seismic moment and radiated seismic energy . The first and the last sequences occurred at the southern border of the Guerrero seismic gap, a region where no significant earthquake () has occurred at least in the last century; whereas the second sequence was located at the northern edge of the same seismic gap. The mean value of the log of radiated seismic energy scaled with the seismic moment, , for this set of earthquakes is . We classify the analyzed events into four regions, two in the southern edge of the gap and two in the northern one. At both ends, there is one region that shows regular values of ( and ), whereas the other one shows low values of ( and ) that could be related to a possible slow‐rupture behavior. These last regions are identified near the trench at southern Guerrero coast and immediately outside the northern end of the seismic gap. The distribution of is spatially heterogeneous along the trench, suggesting variations on the shear strength and coupling at the interface.