Regression models to predict pseudoacceleration response spectra (5% damping), peak ground acceleration (PGA), and peak ground velocity for high‐frequency‐depleted thrust near‐trench events (5.1≤Mw≤8.0; 6≤H≤20 km) in central Mexico, and normal‐faulting inslab earthquakes (5.0<Mw<7.2; 55≤H≤198 km) in southern Mexico were developed using the one‐stage maximum likelihood method. Ground‐motion equations for near‐trench events predict lower ground motions than those predicted by the inslab models, but also lower than relationships based on interplate data for central Mexico. Estimated inslab PGA obtained in this study for southern Mexico is lower than those from inslab events for central Mexico and Central America. Comparison of the inslab response spectra at low frequencies (f<1 Hz) shows that differences in the decay functions for central and southern Mexico are relative minor. High‐frequency ground motion (f>5 Hz) and PGA amplitudes for central Mexico events attenuate faster than in the southern region.