Structural study carried out in southern mid Tunisian Atlas and other regions of Tunisia lead to suggest a structural pattern of horsts, grabens and tilted blocks for the Tunisian palaeo-margin during the Cretaceous period. These tectonic structures are generated by different regimes. Then, during the Aptian and Albian period, the regime is left strike slipping, indicated by E-W sinistral strike slip faults and NE-SW normal faults. During the Turonian-Campanian period, it is right transtensive with ENE-WSW extension, characterized by N120 dextral strike slip faults and N160 normal faults. These kinematics are in accordance with the sinistral relative plate movement between Africa and Eurasia during Aptian-Albian and anti-clockwise movement of Apulia during Turonian-Campanian period.