The Cayman Unconformity, which separates the Pedro Castle Formation (Pliocene) from the underlying Cayman Formation (Miocene), is a sequence boundary that developed during the Messinian, when sea level was at a lowstand due to glaciation in the Southern Hemisphere. By the end of the Messinian, Grand Cayman was an atoll-like island that had an elevated peripheral rim that was up to 41 m above the central depression. The Cayman Formation contains paleocaves and paleosinkholes that were linked to the Cayman Unconformity. The topography on the Cayman Unconformity is attributed to erosional processes, because (1) there is no evidence of carbonates that formed by constructional processes (i.e., reefs, dunes) in the elevated peripheral rim, and (2) there is ample evidence of dissolutional features in the Cayman Formation. The topography developed on the interior of Grand Cayman during the Messinian was uneven. A deep, basin-like depression, with its base as much as 50 m below the peripheral rim, formed on the western part of the island. By comparison, the floor of the depression on the eastern part of the island was 20-30 m higher. The difference in the topography, which is a reflection of the amount of bedrock dissolution, suggests that the effective rainfall was highest over the western part of the island. The relief on the Cayman Unconformity and associated structures shows that base level during the Messinian karst development was at least 41 m below present-day sea level. This is also provides an estimate of the Messinian lowstand position because the base level in oceanic karst settings is usually controlled by sea level.