––For the first time in the last 35 years, hydrogeochemical data on pre-Jurassic complexes in West Siberia have been generalized. Groundwater and brines of Cl–Na and Cl–HCO3–Na type with total salinity (TDS) varying from 4 to 330 g/L are found to be widespread in the area under study, with the former type dominating. A detailed analysis of the hydrogeochemical data allowed us to assume the presence of three genetic groups of groundwater and brines in the hydrogeologic section: (1) sedimentogenic, (2) lithogenic (revived) and ancient infiltrogenic, and (3) condensatogenic. An integrated analysis of coefficients rNa/rCl, Ca/Cl, (Br/Cl)·10–3, and (Sr/Cl)·10–3 and integrated index S of brine metamorphization in the Siberian sedimentary basins has corroborated the fact that groundwater and brines in West Siberia are at the initial stage of metamorphization of their chemical composition. Groundwater and brines in the studied Siberian sedimentary basins show an increase in the degree of metamorphization (catagenetic changes) of their chemical composition in transition from the areas of igneous and metamorphic deposits at the base of the Meso–Cenozoic sedimentary cover of the young West Siberian sedimentary basin to the structures of the ancient Siberian Platform, where ultrastrong Ca–Na and Ca chloride brines are widespread.