We present results of geochemical studies of organic matter of the Jurassic–Cretaceous deposits in the west of the Yenisei–Khatanga regional trough. The studies were carried out on a representative set of well cores by a complex of modern organic-geochemistry methods (determination of organic-carbon content in rocks, pyrolysis, estimation of the carbon isotope composition in the kerogen of rocks, extraction, liquid and gas–liquid chromatography, and chromato-mass spectrometry). Based on the distribution of biomarkers in the studied bitumens and pyrolysis of rocks, two groups of the samples were recognized: with terrigenous (type III) and marine (type II) organic matter. The terrigenous bitumens are characterized by a low hydrogen index (HI) and a predominance of hydrocarbons C29 among steranes and C19 and C20 among tricyclanes. The marine bitumens, revealed in stratigraphic analogs of the Bazhenovo Formation and in the Malyshevka, Nizhnyaya Kheta, and Shuratovka Formations, show an even distribution of sterane homologues and a predominance of medium-molecular tricyclanes. The Pr/Ph and C35/C34 ratios and the presence of diahopanes testify to the burial of organic matter in suboxidizing sea coast environments. In the Yanov Stan (J3–K1), Gol’chikha (J2–K1), and, to a lesser extent, Malyshevka (J2), Nizhnyaya Kheta, and Shuratovka (K1) Formations, we have recognized widespread stratigraphic levels with marine organic matter of rocks. Its contents and degree of maturity permit these rocks to be considered oil-generating.