Paragenetic, textural, and chemical characteristics of columbite-tantalite minerals are examined as steps towards identifying the metallogenetic processes of their host granitoids. Columbite-tantalite-bearing granitoids of the Eastern Desert province of Egypt can be categorized into: (i) metaluminous alkali granites: (ii) peraluminous Li-albite granites: and (iii) metasomatized biotite and/or muscovite granite (i.e. apogranites). Columbite of the alkali granite is of FeNb 2 O 6 composition and associated with annite. The low F and Li contents of the associated mica precludes the important role of these volatile elements during the late stage of evolution of the alkali granites, thus delaying fractionation of Mn over Fe and Ta over Nb. Compositionally, columbite-tantalite of the Li-albite granites is constrained between MnNb 2 O 6 and MnTa 2 O 6 (the Ta/(Nb-Ta) atom . ratio ranges between 0.10 and 0.80). This low to high ratio and the association of columbite-tantalite with topaz, fluorite and lithian micas (in the series zinnwaldite-white mica) indicate a higher solubility for Ta-fluoride complex compounds and their more stabilized state at lower temperatures in Li- and F-rich sodic melts. The columbite-tantalite commonly exhibits a mottled or patchy zoned texture with the rims consistently higher in Ta than the cores, reflecting the later effect of a corrosive supercritical vapour phase. The columbites of metasomatized granites range in composition between FeNb 2 O 6 and MnNb 2 O 6 . They are characterized by high Ti and U, and low Ta contents (the Ta/(Nb+Ta) atom . ranges between 0.01 and 0.15), indicating deposition from alkaline (K (super +) , Na (super +) -rich), and relatively high-temperature interacting fluids. However, the Mn-enriched columbites are commonly encountered in the apical parts of the apogranites and formed in response to high mu KF and mu LiF required for stabilizing the associated Li-siderophyllite, or zinnwaldite. Columbites of the apogranites commonly exhibit progressive (either normal or reverse) zoning which can be attributed to the disequilibrium conditions (e.g. sudden change in the pH) between the growing crystal and the solutions.