Analysis of the interaction of dislocations with bubbles in quartz indicates that the distribution of bubbles during deformation is critically important to the deformation of quartz by dislocation processes. The estimated stress necessary to ensure large scale dislocation movement in inclusion rich quartz (bubbles and voids in the case considered here) is higher than the predicted stresses available during geological creep. Consequently dislocations are likely to remain attached to the bubbles for long periods of time and thus the strain rate of dislocation creep is likely to be strongly influenced by the rate at which the bubble-dislocation system can migrate. Bubbles can also affect the recrystallization of quartz by inhibiting the movement of sub-grain walls and may reduce the size of sub-grains. Finally, it is suggested that the stability and distribution of bubbles in quartz should be considered as an important factor in quartz deformation.