The non-coplanar cross-buried pipelines are a common way of pipeline wiring. In order to investigate the magnetic anomaly characteristics of the non-coplanar cross-buried pipelines and guide the site operation, the influences of a series of factors on the magnetic anomaly of the non-coplanar cross-buried pipelines are analyzed. Based on the principle of magnetic dipole construction, a forward model is established for the magnetic anomaly characteristics of the subsurface non-coplanar cross-buried pipelines. The basic characteristics of magnetic anomaly for the non-coplanar cross-buried pipelines are defined. The influences of geomagnetic parameters (geomagnetic intensity, geomagnetic inclination, and geomagnetic declination), pipeline parameters (thickness, magnetic susceptibility), and cross angle of pipelines on the characteristics of magnetic anomalies are analyzed. The results show that the shape of the total magnetic anomaly is mainly affected by the magnetic inclination, and the curve of magnetic anomaly at ±I site shows some symmetry. The amplitude is approximately linearly affected by the total geomagnetic field, magnetic declination, pipeline thickness, material magnetic susceptibility, and pipeline cross angle. There is a periodic change of the amplitude with the increase of geomagnetic inclination (−90°–>90°). The crest-trough distance is mainly affected by geomagnetic inclination, magnetic declination, thickness, magnetic susceptibility, and pipeline cross angle. A more accurate measurement can be achieved if the direction of the pipelines is roughly measured and then the number of measurement points is augmented near the intersection of pipelines and the measurement lines. Present work obtains the equivalent magnetic dipole units by segmenting pipelines. The magnetic anomaly characteristics of non-coplanar crossed iron pipelines are successfully simulated. The numerical results are in accordance with the experimental analysis.