Seismic amplitude has played a critical role in the exploration and exploitation of hydrocarbon in West Africa. Class 3 and 2 amplitude variation with offset (AVO) was extensively used as a direct hydrocarbon indicator and reservoir prediction tool in Neogene assets. As exploration advanced to deeper targets with class 1 AVO seismic character, the usage of seismic amplitude for reservoir presence and quality prediction became challenged. To overcome this obstacle, (1) we used seismic geomorphology to infer reservoir presence and precisely target geophysical analysis on reservoir prone intervals, (2) we applied rigorous prestack data preparation to ensure the accuracy and precision of AVO simultaneous inversion for reservoir quality prediction, and (3) we used lateral statistic method to sum up AVO behavior in regions of contrasts to infer reservoir quality changes. We have evaluated a case study in which the use of the above three techniques resulted in confident prediction of reservoir presence and quality. Our results reduced the uncertainty around the biggest risk element in reservoir among the source, charge, and trap mechanism in the prospecting area. This work ultimately made a significant contribution toward a confident resource booking.