We have developed and validated a new approach to upscale lithology and porosity-type fractions from thin sections to cores using dual energy and multiscale computed tomography (CT). A new rock-typing approach (genetic rock typing [GRT]) is proposed to upscale ⇋diagenetic mineral and diagenetic pore-type fractions, from thin sections to the core domain, eventually to create a diagenesis and porosity types logs. An extensive set of short cores from Mason County (Texas) provides a representative sample set of Late Cambrian microbial buildups and their interbuildup sediments to test the GRT approach. GRTs were defined by using a dolomite log as a proxy for diagenesis and the average percentage of dolomite from each observed depositional facies (buildup interior, buildup rind, and interbuildup sediment) as a cutoff. Dolomite, diagenetic calcite, and diagenetic porosity fractions are summed to form a diagenesis log, which captures depositional facies and the diagenetic overprint at a 0.5 mm resolution. The diagenesis log was subdivided based on the number of pore-throat size classes within each GRT and provided a framework to distribute porosity-type fractions from thin sections to log form. A high correlation coefficient is observed when the predicted extent of diagenetic alteration from the log is compared with that quantified for each thin section using image processing (). Multiscale CT imaging and dual-energy-derived logs could be directly linked to well-log photoelectric factor and bulk-density logs. This approach thus has the ability to span six orders of magnitude in resolution (500–0.0005 mm). The diagenesis log can be used to extrapolate porosity-type fractions from thin sections to logs, from which qualitative geologic interpretations can be generally translated into quantitative values.