The varied terrain and complex subsurface structure in the foothill segment of fold and thrust belts results in low-quality seismic data. Therefore, a structural model built only on the basis of seismic will have low reliability and be nonunique. To solve these problems, we have developed a comprehensive modeling method for foothill zones that combines gravity, magnetic (MT), electric, and seismic data. Information from gravity, MT, electric, and seismic data is fully used in each step of modeling. This reduces the nonuniqueness and guarantees the rationality and reliability of the tectonic model. The core of this procedure is simultaneous joint inversing gravity, MT, electric, and seismic multiparameters, which improves the accuracy of velocity model and results in a higher quality of seismic image. The Hala’alate Mountain area in the Junggar Basin, western China, is chosen as the application place, and the process of modeling is evaluated in detail; the structural model is proven to be correct by drilling data. Our method is more accurate and reliable than methods only using seismic data to build a geologic model in foothill zones.