The modeling and prediction of transport and elastic properties for sandstones are critical steps in the exploration and appraisal of hydrocarbon reservoirs, particularly in deepwater settings where seismic data are abundant and well costs are high. Reliable multiphysics modeling of reservoir rocks requires robust models that respect the underlying geologic character and microstructure of the geomaterial and honor the measured properties. We have developed a case study that integrates traditional laboratory measurements with computational methods to quantify and relate physical properties of reservoir sandstones. We evaluate the complementary use of digital rock simulations as a practical technology that adds physical insight into the development and calibration of rock-property relationships. We also determine the challenges faced while applying digital rock physics to interpret laboratory data, and the steps taken to overcome those limitations. Combining physical and computational methods, we achieve an improved understanding of the link between geologic properties (sorting, microporosity) with transport (single-phase permeability, electrical conductivity) and elastic properties (moduli). Combining physical measurements with numerical computations has enhanced our understanding of multiphysics relationships in a heterogeneous sandstone reservoir.