Gravity measurements and reinterpretations of previously released seismic lines were made, focusing on the provincial border between neighboring provinces San Juan and Mendoza. A Bouguer anomaly map was obtained after the processing of gravimetric data, which were previously filtered, to obtain the Bouguer residual anomalies used for studying the geologic structures located on the upper crust. The analysis of these Bouguer residual anomalies allowed identification of the Jocolí Basin in a foreland position within a triangle zone at the boundary of the Precordillera fold-and-thrust belt with the Sierras Pampeanas thick-skinned foreland province. The seismic images allowed interpretation of three horizons: Paleozoic, Triassic, and Tertiary-Quaternary ages. The authors have reinterpreted the seismic and well data and reconstructed gravity models for the area under study aiming at unraveling the deep structure of the region and identifying features with potential for oil and gas exploration.