Calcite cement often occurs locally, forming thin layers of calcite-cemented sandstone characterized by high seismic velocities and densities. Because of their strong impedance contrast with the surrounding rock, calcite-cemented intervals produce detectable seismic reflection signals that may interfere with target reflections at the top of a reservoir. In this case, the amplitude-variation-with-offset (AVO) of the effective seismic signature will be altered and may even create a false hydrocarbon indication. From the Monte Carlo simulation, we find that the presence of thin calcite-cemented beds increases the uncertainty of the Bayesian pore-fluid classification based on the AVO attributes intercept and gradient. In the case example of a North Sea turbiditic oil and gas field, the probability of a false-positive hydrocarbon indication increases from 3%–5% to 18%–21% assuming an equal probability of the occurrence of brine, oil, and gas. The results confirm that calcite-cemented beds can create a pitfall in AVO analysis. Realistic estimates of the AVO uncertainty are crucial for the risk assessment of well placement decisions.