3D seismic data provide new insights on c. 2 km thick Cenozoic post-transform slope sediments and fluid-flow phenomena along the Nigerian Transform Margin. The study documents large-scale mass-transport deposits (MTDs), deep-water channels, sediment waves, and a range of fluid-flow phenomena such as pockmarks, pipes, seabed mound and gas hydrates. They are observed from Pliocene-aged sediments and distributed above structural highs, regional faults, and active and relict deep-water channels in the eastern part of the area, closest to the Niger Delta cone. The fluid-flow features are interpreted to be indicative of an active petroleum system in the deeper subsurface and from fluid migration along planes of deep-seated faults. MTDs are mapped at multiple levels and the volume of failed sediments increased through time within the western part of the study area. The repeated and increased volume of MTDs in the area is attributed to an increased rate of sedimentation through time and slope gradient during the late Cenozoic. The presence of repeated MTDs and fluid-flow phenomena on the Nigerian Transform Margin has implications for installations of offshore facilities as they constitute potential geohazards. The study also documents, for the first time, polygonal fault systems offshore Nigeria.