Volcán de Colima, one of the most active volcanoes in Mexico, experienced at least nine flank failures during the last 30 000 years, with catastrophic effects on the environment that implies the formation of temporary dams where lacustrine sediments accumulated for hundreds of years. These lacustrine sequences preserve an exceptional record from which to reconstruct the effect of subsequent volcanic eruptions and, eventually, contemporary environmental and climatic conditions. Here we analyse an Early Holocene lacustrine sequence, named ‘Gypsum King’, which accumulated in a short-lived temporary lake, likely formed by emplacement of the 10 755–11 230 cal years BP Mesa-Yerbabuena debris avalanche. Through detailed analysis of the 1.8 m thick lacustrine sequence (¹⁴C ages, sulfur content, grain size), it was possible to identify the 8.2 kyr global climate event and better constrain the Early Holocene main sub-plinian to plinian eruptions of Volcán de Colima. The results presented here highlight the potential to explore sulfur content and abrupt change in grain size in lacustrine sediments as additional proxies to better constrain eruptive phases in volcanic environments. Finally, the Gypsum King sequence provides the first evidence of the 8.2 kyr global climate event along the Eastern tropical Pacific Coast.