The progressive closure of the Neotethys Ocean had a profound impact on the ocean-climate system during the Cenozoic. In this perspective, Turkey represents a key area for studying the climate evolution during the Eocene, because it was located at the gateway between the Neotethys and the Atlantic Ocean. Here, we present a high-resolution integrated magnetobiostratigraphic record of a new middle Eocene sedimentary section from the Elazığ Province, eastern Turkey. The continuous, undisturbed, and undeformed sedimentary record, together with preserved geomagnetic signal and fossil assemblages, allows the establishment of a detailed age model, which spans from the upper part of chron C19n.1r to the base of chron C17n.1n (42.4–37.8 Ma). Field observations and paleontological and paleomagnetic data show that the section has not been affected by the widespread tectonic deformation that characterizes the region. We suggest that the magnetostratigraphically and biostratigraphically calibrated Baskil section represents a new, outstanding shallow- to deep-marine sequence where paleoceanographic and paleogeographic studies can be conducted to understand the middle Eocene climate evolution.