Assessment of seismic hazards in southern California may be improved with more accurate characterization of the active San Andreas fault strands within the San Gorgonio Pass region. Ongoing debate centers on the activity and geometry of the Mill Creek and Mission Creek strands. Here, we investigate crustal deformation models with six geologically plausible geometries of the Mill Creek and Mission Creek strands. Model results suggest that differences in active fault geometry along the San Andreas fault impact slip rates along the San Jacinto fault by up to 3 mm/yr. Each model fits many but none fits all of the available geologic strike-slip rates. The calculated misfits to the geologic strike-slip rates reveal two best-fitting models: the Inactive Mill Creek model and the West Mill Creek model, which incorporate active portions of the Mill Creek, Mission Creek, and Galena Peak strands, consistent with recent studies. The cumulative strike-slip rates across faults of the two best-fitting models differ from each other by ~5 mm/yr, suggesting that fault slip rates do not always sum to the plate rate. Consequently, kinematic slip budgets should consider off-fault deformation. The two best-fitting models produce uplift patterns with significant differences in the hanging walls of dipping faults. New uplift rate data in these regions and additional geologic slip rates along the northern fault strands could further support plausible interpretations of active fault configuration. An assessment of the seismic hazard of the region indicates the potential for a rupture through the San Gorgonio Pass region with Mw ~7.8.

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