Volcanic units and their crystals carry a memory of hidden magma reservoirs. Here, through a statistical assessment of a worldwide compilation of volcanic bulk-rock and associated mineral data, we can quantify the proportion of crystals that appear in disequilibrium with their bulk-rock composition, over a large range of temperature conditions and magma types. Minerals in these erupted units are frequently in disequilibrium with their bulk-rock chemistries, particularly in crystal-rich material of intermediate composition (~dacites, with up to 60%–80% disequilibrium). The disequilibrium crystals can be grouped in two categories: (1) dominantly more evolved than their hosts (in mafic magmas), or (2) dominantly less evolved than their hosts (in intermediate and silicic magmas). We suggest that (1) crystal accumulation, and (2) mineral entrainment from preexisting shallower mush zones, together explain the presence of more-evolved crystals in mafic systems, while mingling/mixing between resident intermediate to silicic magmas and more mafic recharges in upper crustal mush zones accounts for dominantly less-evolved character of minerals in intermediate to silicic volcanic rocks. The transition between the two domains occurs in the mid-crust, at intermediate composition and temperature (~1000–1100 °C), coincident with the SiO2 increase and FeOtot/density decrease seen in evolving magmas. This statistical information supports other petrological and geophysical evidence indicating dominantly mafic lower crustal mush zones, producing intermediate magmas that then ascend to shallower levels (building a granodioritic upper crust) and sometimes differentiate further to rhyolite/granite/pegmatite.