Structural development of the Altiplano during the past 10 m.y. involved crustal thickening and enhanced curvature of the central Andes. Oroclinal bending of 30° explains reasonably the pattern of vertical-axis rotations observed from units with ages 10 to 30 Ma. New paleomagnetic data from Late Cretaceous through Paleocene strata of southeastern Peru and the Eastern Cordillera of Bolivia document rotations that are also counterclockwise on the north limb of the orocline and clockwise on the south limb. However, the rotations of units with ages 30 to 70 Ma are more variable; nearby areas have undergone differential vertical-axis rotations of up to 60° . These larger rotations that have affected 30–70 Ma units in the central Andes may represent (1) local rotations during late Oligocene to present orogeny, (2) local rotations during Eocene orogeny, and/or (3) oroclinal bending during Eocene orogency.