The Honey Lake fault zone, a major right-lateral fault in the Basin and Range province of eastern California, is one of a broad system of faults that accommodate some of the relative motion between the Pacific and North American plates. These right-lateral faults may have significantly higher slip rates, and thus greater earthquake hazards, than the normal faults for which the Basin and Range is more commonly known. In the Honey Lake Valley, the fault forms a 50-km-long zone of landforms typical of active strike-slip faults. Right-lateral offset of an incised creek channel is used to estimate a Holocene slip rate of between 1.1 and 2.6 mm/yr. A fault exposure in Holocene alluvium shows evidence for at least four late Holocene surface-faulting earthquakes.