Fluids expelled from the Arkoma basin in response to Late Pennsylvanian–Early Permian orogenesis in the Ouachita foldbelt may have been ultimately responsible for formation of the Mississippi Valley–type lead-zinc deposits in the Ozark region of Missouri, Arkansas, Kansas, and Oklahoma. Fluid inclusions in both mineralized and barren rock record the passage of hot, saline fluids regionally throughout most of the Paleozoic section in the Ozarks. Dating studies in addition to structural and geologic observations provide further evidence for fluid migration and mineralization approximately coincident with the Ouachita orogeny.

Formation of foreland basins, such as the Arkoma, during convergent tectonism creates conditions exceptionally favorable to the migration of fluids from deep sedimentary basins. Proximity to a basin whose margin has undergone some form of tectonic deformation or uplift may be the unifying factor in the genesis of Mississippi Valley–type deposits in geologically diverse settings.

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