New seismic reflection data in the southwestern part of the New Madrid seismic zone (NMSZ) show that a major zone of disrupted reflectors and a large antiform coincide with a prominent trend of earthquake epicenters between Caruthersville, Missouri, and Marked Tree, Arkansas. We speculate that the antiform may be caused by igneous intrusions. The strong correlation between the seismicity in this trend and the extent of the disrupted zone provides a geologic basis for defining the source zone for large earthquakes in this part of the NMSZ.

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