Ca. 500 Ma orthogneisses and bimodal suites are widespread along the northern part of the Bohemian Massif (central European Variscides) and are interpreted to document intense magmatism during a continental break-up episode along the northern periphery of Gondwana. Based on geological setting, and geochemical and isotopic evidence, these felsic igneous rocks record the generation of: (1) magmas of pure or predominantly crustal derivation, represented by minor extrusives and much more voluminous orthogneisses similar to S-type granitoids; (2) subordinate magmas of exclusively mantle origin (ranging from within-plate alkali trachytes to oceanic plagiogranites) corresponding to felsic derivatives of associated basalts; and (3)...