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Recent studies have presented the relationship of various geological, ground-water chemistry, and other environmental factors to death rates for cardiovascular-renal (CVR) and other chronic diseases in the same geographic areas. Several studies report a negative correlation of hardness in the drinking water with CVR diseases death rates. Other studies do not support the hypothesis of a protective role for hard water. In view of the complexity of the environment, other variables in the physical environment, as well as cultural and socioeconomic factors, also require careful consideration.

In Indiana, a variation in CVR diseases death rates follows the Wisconsinan glacial boundary...

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