Abstract The Pliocene fossiliferous succession of the Volterra hill, a prominent place in Tuscany, Italy and, since the Renaissance, the site of important archaeological finds of the ancient Etruscan civilization, has formed the object of enquiry over six centuries of research on the inner nature of the Earth system. The works of Restoro d'Arezzo, Leonardo da Vinci, Nicolaus Steno, Giovanni Targioni, Nicolas Desmarest, Giambattista Brocchi, Alexandre Brongniart and Charles Lyell testify to the early recognition through fieldwork that those strata with seashells had formed at the bottom of the sea. This interpretation served different approaches to knowledge. Restoro, Leonardo and Steno, spanning nearly four centuries in the history of science (1282–1669), including the ‘Copernican Revolution’ and the start of the Modern Age, relied also on textual sources and trusted a speculative model of the Earth's interior, so that at Volterra they focused on vertical movements of the earth–water system. The authors of the eighteenth and nineteenth centuries abandoned pre-built young-Earth models and emphasized the geography of ancient Tuscany. Brocchi, Brongniart and Lyell promoted the taxonomic use of seashells to correlate rocks across Europe. This place deserves higher standards of valorization to promote understanding of the history and sociology of ideas.