Abstract The Cambrian Atlas – Ossa–Morena – North Armorican Rift extended along West Gondwana from the end of the Pan-African and Cadomian orogenies until the diachronous beginning of drift conditions related to the opening of the Rheic Ocean. The along-axis rift cross-cut the western parts of the Anti-Atlas, High Atlas and Coastal Meseta, which were linked to the Ossa–Morena Zone and the North Armorican Domain, whereas several joint tectonic branches connected with off-axis rift transects of the Central Iberian, West Asturian–Leonese and Cantabrian zones (Iberian Massif), the Central and South Armorican domains, the Occitan Domain, the Pyrenees, and southern Sardinia. The pre-rift unconformity, post-dating the orogenic collapse, is characterized by initial (half-)graben development and subsequent infill, with slope-related breccias and conglomerates controlled by the denudation of surrounding uplands. Synrift pulses show regional extension and are distinctly identifiable on the top of rift shoulders, recording episodes of carbonate production due to their association with karst and hydrothermal processes. The break-up unconformity ranges from volcanic-free angular discordances and paraconformities to generalized uplift and denudation of subaerially exposed areas, associated with the onset of granite-dominant large igneous provinces (LIPs). The Furongian–Tremadocian (Toledanian) and Ordovician (Sardic) phases have been interpreted as due to: (i) Andean-type subduction magmatism reaching the crust in an arc–back-arc setting; (ii) post-collisional decompression melting without significant mantle involvement; and (iii) partial melting of the lower continental crust affected by the underplating of hot mafic magmas linked to superplumes.