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osteocalcin

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Journal Article
Journal: Geology
Published: 01 December 2002
Geology (2002) 30 (12): 1099-1102.
...Christina M. Nielsen-Marsh; Peggy H. Ostrom; Hasand Gandhi; Beth Shapiro; Alan Cooper; Peter V. Hauschka; Matthew J. Collins AbstractWe report the first complete sequences of the protein osteocalcin from small amounts (20 mg) of two bison bone (Bison priscus) dated to older than 55.6 ka and older...
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Journal Article
Journal: Geology
Published: 01 December 2000
Geology (2000) 28 (12): 1139-1142.
...M.J. Collins; A.M. Gernaey; C.M. Nielsen-Marsh; C. Vermeer; P. Westbroek AbstractOur claim, published in this journal, for successful immunodetection of the protein osteocalcin in dinosaur bone has been challenged on the grounds that the findings are inconsistent with the kinetics of decomposition...
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Journal Article
Journal: Geology
Published: 01 October 1992
Geology (1992) 20 (10): 871-874.
...Gerard Muyzer; Philip Sandberg; Marjo H.J. Knapen; Cees Vermeer; Matthew Collins; Peter Westbroek AbstractTwo different immunological assays were used to identify the remains of a bone matrix protein, osteocalcin (OC), in the bones of dinosaurs and other fossil vertebrates. Antibodies raised...
Image
Figure 2. Comparative rates of loss of <b>osteocalcin</b> (OC) mid-region (Pro 15 ...
in > Geology
Published: 01 December 2000
Figure 2. Comparative rates of loss of osteocalcin (OC) mid-region (Pro 15 -Glu 31 ) in bone powder heated at 75 °C, 85 °C, 95 °C. Inset shows expansion of data for first 30 days.
Image
Figure 4. Survival of <b>osteocalcin</b> mid-region in Neolithic bones (Chassean c...
in > Geology
Published: 01 December 2000
Figure 4. Survival of osteocalcin mid-region in Neolithic bones (Chassean culture, 6 ka, from Bercy [Paris]. Bones at this site were preserved across paleochannel and display variable preservation; osteocalcin survival is also extremely variable. When plotted against extent of apatite
Journal Article
Journal: PALAIOS
Published: 01 February 2002
PALAIOS (2002) 17 (1): 36-49.
.... The relative abundance of amino acids of collagen from heated bone differs by less than 10% from that of unheated collagen. Protein preservation is indicated by matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) that strongly indicates a portion of the original osteocalcin exists intact...
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Journal Article
Published: 01 November 1997
Bulletin de la Société Géologique de France (1997) 168 (6): 759-766.
... bovine collagen and osteocalcin antibodies failed to reveal unambiguously these proteins. These results are discussed in relation to causal agents of fossilization occurring in the Holzmaden site. GeoRef, Copyright 2004, American Geological Institute. 1997 ...
Image
Figure 1. Comparison of survival rates in bone powders (open symbols) and r...
in > Geology
Published: 01 December 2000
Figure 1. Comparison of survival rates in bone powders (open symbols) and reconstituted “bone” (filled symbols) at 75 °C of different osteocalcin epitopes. Note order of magnitude difference in time scales of two experiments and slow rate of small residual fraction of Gla-rich mid-region
Image
Figure 2. Matrix-assisted laser desorption ionization mass spectrometry (MA...
in > Geology
Published: 01 December 2002
Figure 2. Matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) of osteocalcin tryptic digests. Mass spectra for (A) modern bison and (B) older than 58.9 ka bison obtained using 4-HCCA represent MH + ions of proteolytic peptides with fully decarboxylated Gla. Data for (C) modern
Image
Figure 3. Arrhenius plot to illustrate comparative rates of decomposition o...
in > Geology
Published: 01 December 2000
Figure 3. Arrhenius plot to illustrate comparative rates of decomposition of osteocalcin (OC) epitopes in both reconstituted “bone” (filled symbols) and bone powder (open symbols). These results are compared with reported survival of immunological signatures from serum proteins (hemoglobin; albumin
Image
Figure 1. Matrix-assisted laser desorption ionization mass spectrometry (MA...
in > Geology
Published: 01 December 2002
for (A) modern bison and (B) older than 55.6 ka bison. C: rp-HPLC of older than 58.9 ka bison peak extract eluted from gravity column; arrow indicates ∼11 min osteocalcin peak
Image
Figure 3. Post-source decay (PSD) of tryptic peptide 1–19 from older than 5...
in > Geology
Published: 01 December 2002
Figure 3. Post-source decay (PSD) of tryptic peptide 1–19 from older than 55.6 ka fossil bison osteocalcin. Precursor ion, MH + , is represented by peak at the highest m / z (2066). Metastable decay products from cleavage of peptide backbone were labeled using Roepstorrf nomenclature ( Roepstorff
Journal Article
Published: 01 July 2018
Clays and Clay Minerals (2018) 66 (3): 274-285.
... and secretion of various hormones that include osteocalcin, testosterone, thyroid hormones, insulin-like growth factor-1, and insulin, and Zn plays a vital role in the growth and development of animals ( Giugliano and Millward, 1984 ; Fukada et al. , 2011 ). Dietary supplementation with Zn as ZnSO 4 has been...
FIGURES
Journal Article
Journal: Elements
Published: 01 December 2007
Elements (2007) 3 (6): 385-391.
... in bone and dentin also change with time. Initially, the mineral crystals are formed in an environment rich in the so-called SIBLING (Small Integrin-Binding LIgand N-linked Glycoprotein) proteins. As bone crystals grow, there is greater association with proteins, such as osteocalcin, that regulate...
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Journal Article
Published: 01 November 2017
American Mineralogist (2017) 102 (11): 2170-2179.
..., and tested for expression of various biochemical indicators for cell proliferation and cell vitality, such as levels of osteocalcin, osteonectin, osteopontin, alkaline phosphatase, and bone sialoprotein. Compositions conforming specifically to CaTiZr 3 (PO 4 ) 6 displayed maximum osteoblastic...
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Journal Article
Published: 01 May 2002
Journal of Paleontology (2002) 76 (3): 518-528.
... molecules, such as osteopontin, osteocalcin, and bone sialoprotein, make up the remainder ( Murray and Keeley, 1996 ). Fish bone is high in hydroxyproline and glycine ( Prostak et al., 1992 ). Enameloid, the outer covering of most living fish teeth, is based largely on collagen, and contains high levels...
FIGURES
Journal Article
Published: 01 January 2006
Reviews in Mineralogy and Geochemistry (2006) 64 (1): 283-313.
..., alkaline phosphatase (ALP). Another important protein that can be evaluated is osteocalcin (OCN). This is a non-collagenous extracellular matrix protein, and its presence is indicative of the beginning of bone mineralization (HAP precipitation). West and Wallace (1993) and Wallace et al. (1993) were...
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Journal Article
Published: 03 January 2003
Reviews in Mineralogy and Geochemistry (2003) 54 (1): 249-289.
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