Abstract The deposits of the Norilsk-Talnakh region in northern Russian are some of the richest in the world and the type example of a magmatic sulfide deposit associated with a large igneous province. The ores—massive and disseminated, Cu-, Ni-, and PGE-rich sulfides—are hosted in small mafic intrusions that intrude the sedimentary sequence that immediately underlies the Siberian flood volcanic sequence. In general the origin of the deposits is relatively well understood. Magma, probably from a large mantle plume, interacted with crustal rocks during its passage to the surface. The assimilation of evaporites led to the addition of sulfur and to the segregation of ore metal-rich sulfides that accumulated in the lower parts of shallow-level intrusions. Aspects of the model that require clarification are (1) the role of lithosphere architecture in the localization of the ore deposits, (2) the exact relationship between the assimilation of crustal rocks and the segregation of sulfide, and (3) the mechanism of transport and accumulation of the sulfides.