Abstract Recent analysis of data for the Noril'sk region defines new exploration criteria that can be used to assist in the discovery of Noril'sk- type Ni-Cu-platinum group elements (PGE) deposits. Volcanic-plutonic depressions are identified as ore-controlling structures that are formed during the discharge of lava from magma chambers. Deep seismic sounding, magnetic, and gravimetric data outline the distribution of these depressions. They appear to be primary regional structures controlling placement of intrusions in the region. They are confined to a zone of continued pericratonic subsidence located in shoulder structures of a Permo-Triassic rift system. Main structural elements within the Earth's crust underlying the volcanic-plutonic depressions have been identified. Magnetic and gravimetric signatures of the Noril'sk volcanic-plutonic depressions and mineralized intrusions can be used as exploration guides. These data provide regional and local exploration guides that are outlined for use in the search for Noril'sk-style deposits in other large igneous provinces. The internal structure, zoning in intrusions, and host rock alteration can also help determine the potential for significant mineralization in the intrusions. The distribution of sulfides, copper, nickel, and PGE minerals in or near the intrusions and their relation to the shape of the intrusion help to establish trends in ore localization and is a valuable guide for drilling. The distribution of PGE concentrations in the Talnakh intrusion indicates strong positive correlation with the distribution of copper and nickel grades.