Abstract The Zhoukoudian (Choukoutien) site, which was excavated in 1921, is one of the most important ancient human sites in China and in the world as well. From the perspective of the history of transnational science, this paper summarizes the history of the excavation of Zhoukoudian and the research that has been done into related fossil and human remains. It argues that Zhoukoudian was the birthplace of palaeoanthropology and the stimulus for the establishment of Paleolithic archaeology as a field in China. The Zhoukoudian site preserves traces of prehistoric human activities that date from 700 000 to 10 000 years ago, including human fossils, stone artefacts, ornaments and mammalian fossils. Thus, it still remains the most abundant, systematic and valuable site of its kind in the world, as well as being a very important geoheritage site.