Abstract An evaluation of the potential geodynamic connections between the evolution of Paleozoic oceans in NW Gondwana and NE Gondwana is challenging. Until recently, most syntheses emphasized only two Paleozoic oceans (the Proto-Tethys and the Palaeo-Tethys) in the east Tethys realm. However, the discovery of early Paleozoic ophiolites along Palaeo-Tethys sutures located south of Proto-Tethys sutures challenges these traditional views. After a comprehensive review of relevant early Paleozoic tectonomagmatic events, we herein recognize and propose a model for the tectonic evolution of a hitherto unrecognized early Paleozoic ocean, which we call the Proto-Qiangtang Ocean. This ocean was short lived; it opened in the late Cambrian, began to subduct in the Middle Ordovician, and closed diachronously westwards between the Late Ordovician and the middle Silurian. Its closure by middle Silurian time indicates that was a spatially and temporally distinct ocean from the Palaeo-Tethys Ocean. The early tectonic evolution of the Proto-Qiangtang Ocean shares many characteristics with that of the Rheic Ocean. Both opened in the late Cambrian in the back-arc region of the Iapetus–Proto-Tethys Ocean, and the Proto-Qiangtang Ocean is considered to represent the eastern extension of the Rheic Ocean. This correlation has important implications for the Paleozoic tectonic evolution and palaeogeography of northern Gondwana.