Abstract We present a review and synthesis of the tectonic geomorphology along the eastern margin of the Tibetan Plateau adjacent to and north of the Sichuan Basin. Re-evaluation of spatial variations in the form of fluvial longitudinal profiles provides a refined image of the distribution of anomalously steep channels. Three new analyses demonstrate that these variations in channel steepness reflect variations in the locus and rate of differential rock uplift. First, measurements of channel width along trunk streams reveal systematic co-variations in channel hydraulic geometry and slope that suggests channels are dynamically adjusted to spatial variations in erosion rate. Second, recent determinations of the functional relationship between channel steepness indices and erosion rate allow a quantitative estimation of erosion rate from channel profile form. Third, comparison of rock uplift patterns to variations in the distribution of slip associated with the 2008 Wenchuan earthquake confirms that channel gradients reflect differential rock uplift. Our analysis suggests that reactivated fault systems adjacent to the Sichuan Basin are primarily responsible for accommodating differential rock uplift, but that rock uplift northward along the margin is not associated with active faults and is likely sustained by flow and thickening in the deep crust.