Abstract The Palinpinon geothermal field (Negros Island, Philippines) is a high-temperature, liquid-dominated geothermal system. Hydrothermal alteration assemblages in the Nasuji-Sogongon region are associated with the Nasuji pluton and include K silicate (biotite, magnetite), calc-silicate (garnet, clinopyroxene), hypogene advanced argillic (andalusite, zunyite), propylitic (tremolite-actinolite, epidote), and distal illite (smectite, illite) and steam-heated advanced argillic (amorphous silica, kaolinite, alunite) assemblages. Biotite alteration and associated veins formed from magmatic-hydrothermal fluids that had temperatures from 267° to >600°C, salinities of 26 to 56 wt percent NaCl equiv and up to 0.2 wt percent Cu. Hydrothermal biotite ( 40 Ar/ 39 Ar = 0.7–0.6 Ma) and alunite (K-Ar = 0.9–0.8 Ma) formed contemporaneous with the Nasuji pluton ( 40 Ar/ 39 Ar = 0.7–0.3 Ma), implying a genetic link between intrusion emplacement and hydrothermal alteration assemblages. The emplacement of a blind intrusion in the Puhagan area at depths greater than 2.5 km has provided the heat source for present-day geothermal activity. Calc-silicate, biotite, and propylitic alteration zones developed above this intrusion at depths greater than 2 km. Parts of the biotite and propylitic alteration zones are in thermal equilibrium with the present-day geothermal system. The lack of hypogene advanced argillic alteration at Puhagan is interpreted to indicate that magma degassing has been hindered or prevented, possibly due to high lithostatic confining pressures. At <2 km, illite and steam-heated advanced argillic alteration assemblages have overprinted the biotite and hypogene advanced argillic alteration types associated with the Nasuji pluton and are in thermal equilibrium with the present geothermal system. The intimate spatial and temporal relationships between the intrusion emplacement and the styles of alteration at Palinpinon are characteristic of mineral deposits such as, porphyry, skarn, and high- and low-sulfidation epithermal. At Palinpinon, a coupled porphyry high-sulfidation epithermal alteration system formed at 0.9 to 0.8 Ma with a coupled porphyry low-sulfidation epithermal system forming today, demonstrating that these alteration systems can form simultaneously in a single mineral district. However, assays (<0.02 wt % Cu, <0.03 wt % Pb, <0.01 wt % Zn, <0.01 wt % Mo, <8 g/t Ag and <0.05 g/t Au) show that the alteration zones at Palinpinon are barren. This could be due to insufficient fracture permeability, resulting in a lack of adequate focus for high volume fluid flux. Alternatively, it could relate to an insufficient supply of metals in the magmatic-hydrothermal fluids.