Fluvio-deltaic sedimentary systems are of great interest for explorationists because they can form prolific hydrocarbon plays. However, they are also among the most complex and heterogeneous ones encountered in the subsurface, and potential reservoir units are often close to or below seismic resolution. For seismic inversion, it is therefore important to integrate the seismic data with higher resolution constraints obtained from well logs, whereby not only the acoustic properties are used but also the detailed layering characteristics. We have applied two inversion approaches for poststack, time-migrated seismic data to a clinoform sequence in the North Sea. Both methods are recursive trace-based techniques that use well data as a priori constraints but differ in the way they incorporate structural information. One method uses a discrete layer model from the well that is propagated laterally along the clinoform layers, which are modeled as sigmoids. The second method uses a constant sampling rate from the well data and uses horizontal and vertical regularization parameters for lateral propagation. The first method has a low level of parameterization embedded in a geologic framework and is computationally fast. The second method has a much higher degree of parameterization but is flexible enough to detect deviations in the geologic settings of the reservoir; however, there is no explicit geologic significance and the method is computationally much less efficient. Forward seismic modeling of the two inversion results indicates a good match of both methods with the actual seismic data.