Absolute chronology of magma differentiation processes has been a long-desired goal, given its importance in understanding magma chamber dynamics and its connection to a fundamental understanding of the style and frequency of volcanic eruptions. Broad estimates of the duration of magma differentiation and overall crustal residence times have been made based on a variety of indirect approaches, such as physical models of magma chamber cooling, rates of crystal growth and settling, and long-lived radiogenic isotopes. In contrast, combined 231Pa-235U data may provide a robust measure of the time scale of magma differentiation. Based on 231Pa-235U, 230Th-238U and 226Ra-230Th data from Taal volcano, Luzon Arc, Philippine Archipelago, we show that 231Pa-235U data may provide a robust direct measure of the time scale of magma differentiation. A closed-system magma fractionation model gives a 231Pa-235U differentiation time scale in the range of 30 k.y., while the 226Ra-230Th time scale is considerably younger. The time scales are reconciled if we consider either fluid-mixing or magma-mixing models. The fluid-mixing model gives a time scale of differentiation similar to the 231Pa-235U closed-system time scale and is supported by the 230Th-238U data. The magma-mixing model gives a considerably longer time, in the range of 55 k.y. The combined observations support the robustness of the 231Pa-235U chronology, indicating a differentiation time scale in the range of 30 k.y., although this time scale for other volcanoes may vary depending on size and thermal state of the magma chamber. The 226Ra-230Th closed-system model ages, which yield much younger estimates for magma differentiation, are not likely to reflect time scales of magma differentiation.