Carbonate fades of the Greenbrier Group establish the presence of an east-west-trending Mississippian uplift and record the timing of late Paleozoic tectonic movement in the east-central Appalachian basin at the east end of the 38th Parallel fracture zone. This fracture zone has been defined by previous workers from the alignment of igneous intrusive and volcanic rocks, ore mineralization zones, major fault systems, and Landsat lineaments across eastern and central North America. This fracture system is apparently associated with displacement along faults in the Precambrian basement rock. Movement along the fracture zone occurred periodically throughout the Phanerozoic. The lineament may be distinguished both geomorphically (on Landsat imagery and side-looking airborne radar) and stratigraphically. Mississippian tectonic activity along the eastern section of the fracture zone is indicated by anomalous thinning of sediments, facies patterns, and stratigraphic relations of uppermost Devonian to Upper Mississippian strata of the eastern Appalachian Plateau.