The area discussed in this exploration methodology case study is situated along the Sistan Suture Zone where the granitoid suite is a mantle-derived multiphase intrusive complex. One of the characteristics of this region is the presence of large areas of sulfide-bearing, quartz-rich stockwork and pyritic veins. Geochemical findings show that it is limited to the calc-alkaline to shoshonitic series intrusions and is associated with a volcanic arc (I-type) formed within an active continental margin subduction setting. The associated intrusive complex has characteristics consistent with Cu productive porphyries, supported by high K-adakitic Sr/Y, La/Yb, Y and Al2O3/TiO2 geochemical signatures. The stockwork mineralization includes the hypogene (chalcopyrite and bornite), with locally superimposed supergene (covellite, malachite, goethite and hematite) zones. The Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) images (visible-near infrared (VNIR), and shortwave infrared (SWIR) bands) and mixture tuned matched filtering (MTMF) algorithm enable identification of each hydrothermal alteration type, especially where pictures were innovatively classified using a concentration–number (C–N) fractal method. Four alteration types are evident (i.e. phyllic, argillic and propylitic), as well as secondary (supergene) jarosite, that are associated with gossans, which are an indicator of the hypogene pyritic shell. The propylitic alteration envelopes the phyllic and argillic varieties, forming a belt around the pyritic shell; alteration assemblages were confirmed by X-ray powder diffraction (XRD) analysis. Finally, all results show a mineralization alteration pattern within the case study region that is similar to those of known porphyry copper and associated molybdenum- and gold-bearing systems in this region of Iran and worldwide.