Syn-metamorphic quartz + carbonate veins within lower-amphibolite-facies marbles and greenschist-facies metapelites of the O'Kane Canyon (northern Victoria Land, Antarctica) are characterised by fluids of different composition: H2O-CO2-CH4 mixtures (34-44 H2O, 50-61 CO2, 3-6 CH4, in mole %) (Type A), or H2O-CO2-N2 fluids (35-43 H2O, 48-54 CO2, 9-11 N2, in mole %) (Type B). In metapelites, quartz + carbonate veins contain H2O-CO2-CH4 (Type C) fluids, which have a composition (30-68 H2O, 29-64 CO2, 2-6 CH4, in mole %) similar to Type A fluids in marbles. Isochores for both Type A and Type B fluids intersect the estimated peak conditions of 500°C and 3-3.5 kbar, indicating that fluids with different compositions were trapped in the marbles during metamorphic veining. In greenschist-facies metapelites, isochores for Type C fluids cross the metamorphic P-T conditions at 2 kbar and 400°C. Overall isochore distribution indicates early cooling (500-400° C) without significant uplift. For the N2-bearing Type B fluid inclusions, the &13C value of the CO2 is 2.5 ‰ PDB and the δD of H2O is 0 ‰. The δ18O of host vein-quartz is 20.3 ‰, and δ13C of calcite within the host vein and in marble are both −1.5 ‰. In contrast, the δ13C values of carbonate veins containing Type A H2O-CO2-CH4 fluids are lighter (-5.3 ‰) than in the host marble (-2.9 to −1.5 ‰). Type A fluid inclusions have light δ13C CO2 values (0.1 ‰) and δD H2O values (-84 ‰). Type C inclusions also have light δ13C CO2 values (-3.1 ‰), and variable δD H2O (-30 and −98 ‰). Fluid-inclusion and stable-isotope studies indicate that the analysed quartz-calcite veins formed by local processes in a similar structural context. The veins preserved distinct fluid-inclusion and isotopic compositions, indicating diverse sources of fluids: internally derived metamorphic H2O-CO2-N2 mixtures (Type B), and externally derived H2O-CO2 fluids (Types A and C), interpreted in terms of mixing with a magmatic component, probably derived from local granitic rocks.