Chlorite (C)-corrensite (Co)-smectite (S) series minerals occur as vein constituents in the two epithermal ore veins, the Chuetsu and Shuetsu veins of the Todoroki Au-Ag deposit. The characteristics of the C–Co–S series minerals indicate that the clays may be products of direct precipitation from hydrothermal fluids and subsequent mineralogical transformations during and/or after vein formation. The minerals from the Chuetsu vein are characterized by ‘monomineralic’ corrensite showing an extensive distribution throughout the vein, and trioctahedral smectite occurring locally. The Shuetsu vein minerals are characterized by C-Co series minerals which can be divided into three different types: a I type including discrete chlorite with minor amounts of S layers, a II type comprising interstratified C/Co and discrete chlorite, and a III type characterized by segregation structures of C and Co layers. The C-Co series minerals show slightly different spatial distributions in the Shuetsu vein. Different epithermal environments during the vein formations and possible kinetic effects may have played a role in the formation and conversion of Co-C series at the Shuetsu vein and S-Co series at the Chuetsu vein.