The calibration of a portable three-channel gamma-ray spectrometer for in situ analysis of thorium, uranium, and potassium is discussed. A method of regression analysis is suggested as the best means of including all of the data available from the calibration stations. Calibration indicates a nonlinear relation between count rates obtained in the field and concentrations in parts per million obtained from laboratory analysis. The range of radioelement content must be taken into consideration and appropriate sets of calibration constants applied. As an example of the method, calibration constants are calculated for a portable gamma-ray spectrometer using data for the Blind River uranium region of Ontario.