The Thor–Odin dome of the Monashee complex, in the southeastern Canadian Cordillera, comprises Paleoproterozoic basement gneiss with infolds of unconformably overlying rocks of a supracrustal cover sequence and is the deepest exposed structural level in the Omineca belt. Orthogneiss and paragneiss of the basement are migmatitic and contain ubiquitous stromatic leucosome and discrete phenocrystic and pegmatitic vein-type leucosome, which are all interpreted to have formed as a result of in situ melting. The stromatic leucosome is infolded with the country rock (F2), contains a weakly developed foliation, and has a biotite-rich melanosome. The phenocrystic and pegmatitic vein type leucosome crosscut the stromatic leucosome and the transposition foliation (S2). Evidence to support an igneous and anatectic source for the leucosome includes (i) petrography, (ii) major and trace element chemistry, (iii) zircon morphology, and (iv) peak pressure–temperature (P–T) conditions. Sensitive high-resolution ion microprobe (SHRIMP) 206Pb/238U zircon dates range from ca. 56 to 54 Ma and are interpreted to represent the age of leucosome crystallization. Zircon commonly contains discrete ca. 2.6–1.8 Ga cores that are interpreted as detrital grains inherited from the host paragneiss. Anatexis was ongoing by ca. 56 Ma, as a result of regional prograde metamorphism, and was coincident, at least in part, with the formation of the penetrative S2 transposition foliation and large recumbent F2 tight to isoclinal folds. Anatexis continued during F3 and F4 folding. Melting may have continued until ca. 51 Ma, driven by decompression reactions, and was concomitant with the D5 extensional deformation.