The Paleozoic and early Mesozoic rocks of the Greenwood mining camp in southern British Columbia are a part of the Quesnel terrane in the eastern part of the Intermontane Belt of the Canadian Cordillera. Upper Paleozoic rocks include the Knob Hill Group composed of oceanic tholeiitic basalts (with (La/Yb)n ≈ 0.4–1.2), associated with deep ocean sedimentary rocks and serpentinites; the Attwood Group that comprises island-arc tholeiites (with (La/Yb)n ≈ 1–4 and positive εNd values), clastic sedimentary rocks and limestones; and a unit of oceanic gabbros with (La/Yb)n < 0.5. These lithologically defined units occur as tectonically emplaced slivers of oceanic crust probably produced during the closure of the Slide Mountain basin during the Permian. They are unconformably overlain by Middle Triassic calc-alkaline volcanic and sedimentary rocks of the Brooklyn Group. The Brooklyn Group volcanic rocks have characteristics of mature island-arc rocks, including (La/Yb)n ≈ 2.5–4.5 and positive εNd values. The Paleozoic rocks are crosscut by a 200 million years old granodioritic intrusion containing zircon with an Early Proterozoic inheritance age (∼2.4 Ga). By inference, southern Quesnellia may have been well offshore from the ancestral North American margin in the Mississippian, in close proximity to the margin by the Middle Triassic, and contiguous with it by the Early Jurassic. It is suggested that the complex tectonic history of extension and contraction of the southern Canadian Cordillera during the post Middle Jurassic can be extended in south-central British Columbia as far back as the upper Paleozoic.