Sisters Creek Formation is formally defined, stratotypes are established for it, and the time–space chart is updated for the Fraser Lowland, southwestern British Columbia. The Sisters Creek is a Pleistocene formation comprising in situ and reworked organic-rich sediments, and nonorganic silt, sand, and gravel. The formation was deposited during the Port Moody interstade (within the Late Wisconsinan Fraser Glaciation; δ18O stage 2) between the Coquitlam stade (early Fraser Glaciation) and the main Vashon stadial maximum that occurred about 14.5 ka. The Sisters Creek Formation represents a glacial recession in southwestern British Columbia that generally coincided with the timing of the last global glacial maximum. The new time–space chart implies that, in Fraser Lowland, the Fraser Glaciation represents the rapid advances and retreats of glacial lobes issuing from surrounding mountains, which remained ice-covered during interstades.